Current Appointment
Professor of Chemistry, Department of Chemistry
Education
B.S., 1953, Massachusetts Institute of Technology,
Cambridge, MA
Ph.D., 1956, University of Illinois,
Urbana-Champaign, IL
NIH Special Postdoctoral Fellow, 1967-68,
California Institute of Technology, Pasadena, CA
Research Interests
Physical Organic Chemistry. Research interests
include use of nuclear magnetic resonance spectroscopy in studies of the
stereochemistry and conformations of organic molecules, computer applications in
teaching and research, and organic synthesis. Projects have included the study
of nonchair conformations of cyclohexane derivatives, the influence of
electrostatic interactions among polar groups upon conformational equilibria,
and conformational studies of molecules of biological interest. Much of this
work required the synthesis of organic compounds with deuterium and carbon-13 at
specific locations for use in the determination of NMR coupling constants and
relaxation times, and are interpreted in terms of conformational equilibria.
Experimental conformational energies were also compared with those calculated by
use of the methods of computational chemistry. Other projects have involved the
use of computers in teaching organic chemistry. The most ambitious of these
projects was designed to develop an interactive computer program for teaching of
organic synthesis.
Selected Publications
"On CNDO/2-Predicted Charge Alternation," R. D. Stolow, P.
W. Samal and T. W. Giants, J. Amer. Chem. Soc., 1981, 103, 197-199.
"Computer-Assisted Teaching of Organic Synthesis," R. D. Stolow
and L. J. Joncas, J. Chem. Educ., 1980, 57, 868-872.
"Predominance of the Axial Conformation of
4-Methoxy-cyclohexanone," R. D. Stolow and T. W. Giants, Chem. Commun., 1971, 528-530.
"Census of Nonchair Conformations of 2-t-Butylclohexanones," R.
D. Stolow, T. Groom and
M. Gerace, J. Am. Chem. Soc., 1968, 90, 3290-94.
"Intramolecular Hydrogen Bonding in Nonchair Conformations of cis,
cis, cis-2,5-Dialkyl-1,4-cyclohexanediols," R. D. Stolow, P. M. McDonagh, and M.
M. Bonaventura, J. Am. Chem. Soc., 1964, 86, 2165-68.
"A Quantitative Relationship between Dissociation Constants and
Conformational Equilibria - Cylohexanecarboxylic Acids", R. D. Stolow, J. Am.
Chem. Soc., 1959, 81, 5806.
Additional publications can be found HERE. |
